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Kenneth E McMartin Selected Research

diethylene glycol

7/2016Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro.
5/2014Quantitation of diethylene glycol and its metabolites by gas chromatography mass spectrometry or ion chromatography mass spectrometry in rat and human biological samples.
11/2011Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.
10/2011Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.
9/2010Inhibition of metabolism of diethylene glycol prevents target organ toxicity in rats.

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Kenneth E McMartin Research Topics

Disease

13Poisoning
01/2022 - 03/2005
5Acute Kidney Injury (Acute Renal Failure)
01/2022 - 03/2005
5Necrosis
02/2015 - 03/2005
4Acidosis
02/2015 - 03/2005
4Hyperoxaluria (Oxaluria)
01/2013 - 05/2009
3Renal Insufficiency (Renal Failure)
02/2010 - 03/2005
2Mitochondrial Diseases (Mitochondrial Disease)
07/2016 - 08/2013
2Body Weight (Weight, Body)
12/2012 - 10/2004
2Kidney Calculi (Kidney Stone)
09/2010 - 02/2007
2Hemolysis
02/2007 - 03/2005
1Pulmonary Edema
12/2020
1Hypertension (High Blood Pressure)
12/2020
1Brain Diseases (Brain Disorder)
03/2017
1Peripheral Nervous System Diseases (PNS Diseases)
03/2017
1Primary Hyperoxaluria (Oxaluria, Primary)
01/2013
1Melanoma (Melanoma, Malignant)
05/2008
1Experimental Melanoma
05/2008
1Neoplasms (Cancer)
05/2008
1Seizures (Absence Seizure)
04/2002
1Phenylketonurias (Phenylketonuria)
04/2002
1Inborn Genetic Diseases (Disease, Hereditary)
04/2002
1Headache (Headaches)
04/2002
1Burns
08/2000

Drug/Important Bio-Agent (IBA)

14Ethylene Glycol (Monoethylene Glycol)IBA
01/2022 - 10/2004
6Calcium OxalateIBA
01/2013 - 02/2007
5diethylene glycolIBA
07/2016 - 09/2010
4glycolic acid (glycolate)IBA
01/2022 - 03/2005
4diglycolic acidIBA
07/2016 - 11/2011
3aluminum citrateIBA
12/2020 - 02/2007
3SolventsIBA
06/2017 - 11/2011
3CreatinineIBA
02/2015 - 09/2010
2Bicarbonates (Hydrogen Carbonate)IBA
01/2022 - 10/2011
2Fomepizole (Antizol)FDA LinkGeneric
09/2012 - 09/2010
2OxalatesIBA
02/2007 - 03/2005
1Citric Acid (Citrate)FDA LinkGeneric
12/2020
1Pharmaceutical PreparationsIBA
06/2017
1CalciumIBA
07/2016
1EnzymesIBA
02/2015
1GlycogenIBA
02/2015
1Acetic Acid (Vinegar)FDA LinkGeneric
05/2014
1Oxalic Acid (Disodium Oxalate)IBA
05/2014
1Succinate Dehydrogenase (Fumarate Reductase)IBA
08/2013
1NitrogenIBA
12/2012
1Sodium CitrateFDA LinkGeneric
12/2012
1Urea (Carbamide)FDA LinkGeneric
12/2012
1Methanol (Carbinol)IBA
09/2012
1Adenosine Triphosphate (ATP)IBA
11/2011
1AntidotesIBA
09/2010
1Lactic Acid (Lactate)FDA LinkGeneric
04/2009
1Free RadicalsIBA
05/2008
1Proteins (Proteins, Gene)FDA Link
05/2008
1NADPH Oxidases (NAD(P)H oxidase)IBA
05/2008
1Melanins (Melanin)IBA
05/2008
1diphenyleneiodoniumIBA
05/2008
1Microphthalmia-Associated Transcription FactorIBA
05/2008
1glyoxylic acid (glyoxylate)IBA
08/2007
1glycolaldehydeIBA
08/2007
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2007
1ethidium homodimerIBA
02/2007
1Aspartame (NutraSweet)IBA
04/2002
1Phenylalanine (L-Phenylalanine)FDA Link
04/2002
1Essential Amino AcidsIBA
04/2002
1AlcoholsIBA
08/2000

Therapy/Procedure

2Therapeutics
12/2020 - 01/2013
1Renal Dialysis (Hemodialysis)
03/2005